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Volume 19,     Number 2,     Summer 2011

 

OPTIMAL ANTIVIRAL TREATMENT:
A GEOMETRIC PICTURE
ELSA HANSEN AND TROY DAY

Abstract. Despite much debate and numerous studies, the question of how to most effectively administer antiviral treatment during an influenza pandemic is still unanswered. We present some basic models, coupled with simple geometric arguments, to provide insight into this topic. Specifically, we address the question of how best to administer treatment to minimize the outbreak size. Furthermore we consider how a limited supply of drugs and the occurrence of de novo resistance can affect this solution.

 

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