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Volume 17,     Number 2,     Summer 2009

 

A TWO COMPARTMENT MODEL OF A CA1
PYRAMIDAL NEURON
KATIE A. FERGUSON AND SUE ANN CAMPBELL

Abstract. We develop a two compartment, conductance based model for a pyramidal cell in the CA1 region of the hippocampus. One compartment represents the soma and proximal dendrites, while the second represents the distal dendrites. Using numerical simulations we show that our model reproduces various experimentally observed behaviours including a burst of action potentials when the distal dendrite compartment is stimulated. Finally, we study the synchronization of two such neuronal models, coupled by AMPA synapses.

 

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