Volume 17, Number 2, Summer 2009
A TWO COMPARTMENT MODEL OF A CA1
KATIE A. FERGUSON AND SUE ANN CAMPBELL
Abstract. We develop a two compartment, conductance
based model for a pyramidal cell in the CA1 region of the
hippocampus. One compartment represents the soma and
proximal dendrites, while the second represents the distal dendrites.
Using numerical simulations we show that our model
reproduces various experimentally observed behaviours including a
burst of action potentials when the distal dendrite
compartment is stimulated. Finally, we study the synchronization of
two such neuronal models, coupled by AMPA synapses.